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IMMUNOGLOBULIN LIGHT CHAINS, SURROGATE
Descriptors Found:
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DeCS
Descriptor
English
:
Immunoglobulin Light Chains, Surrogate
Descriptor
Spanish
:
Inmunoglobulina de Cadenas Ligeras Subrogadas
Descriptor
Portuguese
:
Cadeias Leves Substitutas da Imunoglobulina
Synonyms
English
:
Surrogate Immunoglobulin Light Chains
Surrogate Light Chains
Tree Number:
D12.776.124.486.485.705.750.775
D12.776.124.486.485.950.750.500
D12.776.124.790.651.705.750.775
D12.776.124.790.651.950.750.500
D12.776.377.715.548.705.750.775
D12.776.377.715.548.950.750.500
D12.776.543.750.705.816.821.750.500
Definition
English
:
An immunoglobulin
light
chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as
light
chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate
light
chains associate with MU
IMMUNOGLOBULIN HEAVY CHAINS
in place of a conventional
immunoglobulin light chains
to form
pre-B cell receptors.
History Note
English
:
2008
Allowable Qualifiers
English
:
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
poisoning
radiation effects
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52787
Unique Identifier:
D054444
Occurrence in VHL
:
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